MR Contrast in Mouse Lymph Nodes with Subcutaneous Administration of Iron Oxide Particles: Size Dependency
نویسندگان
چکیده
منابع مشابه
Dextran-coated superparamagnetic iron oxide, an MR contrast agent for assessing lymph nodes in the head and neck.
PURPOSE To investigate dextran-coated superparamagnetic iron oxide particles (BMS 180549) as an MR contrast agent for assessing lymph nodes. METHODS Five different doses ranging from 0.3 to 1.7 mg Fe/kg were evaluated in five healthy human male subjects as part of a phase 1 clinical study. T1-, T2-, and proton density-weighted spin-echo images as well as multiplanar gradient-echo and spoiled ...
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The accurate identification and characterization of lymph nodes by modern imaging modalities has important therapeutic and prognostic significance for patients with newly diagnosed cancers. The presence of nodal metastases limits the therapeutic options, and it generally indicates a worse prognosis for the patients with nodal metastases. Yet anatomic imaging (CT and MR imaging) is of limited va...
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PURPOSE To compare findings on superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MR) images of the head and neck with those from resected lymph node specimens and to determine the effect of such imaging on surgical planning in patients with histopathologically proved squamous cell carcinoma of the head and neck. MATERIALS AND METHODS Thirty patients underwent MR imaging with no...
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INTRODUCTION MR cellular imaging using iron-oxide-based contrast agents is an attractive technique in cell tracking and monitoring cell therapies. However, one major obstacle of the widespread application of this technique in clinics is the low sensitivity inherently associated with MRI. Therefore, there are a lot of efforts aimed at enhancing the susceptibility effect induced by the iron-oxide...
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Introduction: Size of axillary lymph nodes can be a predictor for breast abnormalities. The agents in the antiperspirants such as Aluminum were observed in the breast biopsy of individual with abnormalities and antiperspirants usage. In this study, the relation between using antiperspirants and the size of axillary lymph nodes were evaluated in Iranian women. Methods: In this study, 120 wo...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medical Sciences
سال: 2011
ISSN: 1880-2206,1347-3182
DOI: 10.2463/mrms.10.219